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NIH – Peripheral Neuropathy
Why Perform a Skin Biopsy on a Patient with Suspected Neuropathy
To diagnose small fiber neuropathy.
To follow progression of the neuropathy and the response to therapy.
To provide documentation, for purposes of insurance coverage, to support recommended treatments.
To confirm the diagnosis of sensory neuropathy in a patient with a compatible clinical presentation but normal electrodiagnostic studies.
To differentiate between length-dependent neuropathy, ganglionopathy, or multifocal neuropathy.
To diagnose vasculitic neuropathy that also involves the skin.
To diagnose amyloid neuropathy in a patient with amyloid skin deposits.
To participate in clinical trial studies where a skin biopsy is used to assess normal or abnormal status of subjects.
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