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FREQUENTLY ASKED QUESTIONS

When is the ENFD test useful?

Epidermal Nerve Fiber Density (ENFD) testing is particularly helpful for patients who have symptoms or signs of neuropathy, and test normal on EMG or nerve conduction studies. This often occurs when the neuropathy predominantly affects the small nerve fibers, as these are not detected in the electro-diagnostic studies. Although the ENFD is the most sensitive test for diagnosing small fiber neuropathy, a normal test does not necessarily exclude the presence of neuropathy.

How does the ENFD test help me?

  • It provides peace of mind in knowing the cause of your pain
  • It provides a quantifiable measure that helps you follow the progression of the neuropathy and your response to therapy
  • It provides documentation in support of recommended diagnostic tests and treatments
  • Occasionally, it helps identify the presence of other factors that are important in treating your condition

What is the skin biopsy procedure?

Your doctor may perform the biopsy in the office during a normal office visit. The skin is numbed with an anesthetic before a small piece of skin is removed with a small tool. Specimens are approximately 3 mm in diameter and 2 mm deep.

Why did my doctor use Therapath for the ENFD test?

Therapath is a specialized pathology lab that principally focuses on neurological related testing. Skin biopsy for ENFD is one of those specific tests. In general, other local and national in-network laboratories do not provide this test.

How do I get my test results?

Therapath will provide your doctor with the results within 14 days after your biopsy has been received at the laboratory. Please make sure to schedule a follow up appointment with your doctor two weeks after the skin biopsy appointment.

Why can’t test results be given directly to the patient?

Laboratory results may only be given to a physician, his or her agent, or other person authorized by law to use the results in the conduct of his or her practice or the fulfillment of official duties. The majority of laboratory test results must be placed in the context of the patient’s condition, medical history and symptoms, by a trained professional. While many patients have the knowledge, experience and good judgment to properly evaluate test results, the data may cause some patients unnecessary confusion, anxiety and sometimes, alarm. Laboratories are required to release test results to the physician ordering the tests so that a full explanation may be provided at the time that the patient receives the test results. (10 NYCRR Subpart 58-1.8)

Will my insurance carrier pay for the ENFD test?

Yes, your insurance carrier will send an Explanation of Benefits (EOB) to you to explain how they processed this claim. Should you have additional unanswered questions, please contact our reimbursement team for assistance.

How do I contact Therapath with additional questions?

Phone: 1-800-681-4338
Mail: 545 West 45th Street, 7th Floor, New York, NY 10036
Email: LaboratoryServices@Therapath.com
Web: www.therapath.com